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\!h read

public function __construct(\Magento\Framework\App\Config\ScopeConfigInterface $scopeConfig) {
    $this->_scopeConfig = $scopeConfig;
}
return $this->scopeConfig->getValue(self::XML_CONFIG_PREFIX . 'title', self::SCOPE);
return $this->scopeConfig->isSetFlag(self::XML_CONFIG_PREFIX . 'debug',self::SCOPE);

\!h write

public function __construct(
    \Magento\Framework\App\Helper\Context $context,
    \Magento\Framework\App\Config\Storage\WriterInterface $configWriter
){
    parent::__construct($context);
    $this->configWriter = $configWriter;
}
$this->configWriter->save(self::XML_CONFIG_PREFIX . 'min_order_total', $amount);