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.list li:first-child {
  color: #f00;
}

.list li:nth-child(2n) {
  font-weight: bold;
}

.list li:last-child {
  color: #f00;
}

<ul class="list">
  <li>Lorem ipsum</li>
  <li>Lorem ipsum</li>
  <li>Lorem ipsum</li>
  <li>Lorem ipsum</li>
  <li>Lorem ipsum</li>
  <li>Lorem ipsum</li>
  <li>Lorem ipsum</li>
</ul>