Using Flask_SQLAlchemy to connect to Azure SQL
#!/usr/bin/env python
import os
import urllib.parse
from flask import Flask
from flask_sqlalchemy import SQLAlchemy
# Configure Database URI:
params = urllib.parse.quote_plus("DRIVER={SQL Server};SERVER=sqlhost.database.windows.net;DATABASE=pythonSQL;UID=username@sqldb;PWD=password56789")
# initialization
app = Flask(__name__)
app.config['SECRET_KEY'] = 'supersecret'
app.config['SQLALCHEMY_DATABASE_URI'] = "mssql+pyodbc:///?odbc_connect=%s" % params
app.config['SQLALCHEMY_COMMIT_ON_TEARDOWN'] = True
# extensions
db = SQLAlchemy(app)