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1. Remove Speech Voices

cd /System/Library/Speech/
sudo rm -rf Voices/*

2. Delete All System Logs in OS X

sudo rm -rf /private/var/log/*

3. Delete QuickLook Caches

sudo rm -rf /private/var/folders/

4. Remove Emacs

sudo rm -rf /usr/share/emacs/

5. Delete tmp Files

/private/var/tmp/

6. Trash the Cache

rm -rf ~/Library/Caches/*