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define('DISABLE_WP_CRON', true);

*/5 * * * * wget -q -O - "http://mydomain.com/wp-cron.php" > /dev/null 2>&1

#Sometimes it might be required to run PHP directly:
*/5 * * * * php /home/$USER/public_html/wp-cron.php

#You can also do it using curl:
*/5 * * * * curl -vs -o /dev/null http://mydomain.com/wp-cron.php > /dev/null 2>&1